The Eye as a
Window to
Human Health

We build and commercialize medical AI systems that transform retinal and anterior segment imaging into actionable diagnostic intelligence — for eye disease and beyond.

Explore AI Models See FH-POISE™ Platform
100 Number of lives touched
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About the Division

A focused AI team embedded in
ophthalmic innovation

Is our flagship AI platform, which comprises of bespoke AI solutions, engineered for analyzing specific ocular and oculomics conditions.

Each such solution is independent of each other but shares common architecture that enable ease of use and integration

When you choose FH-POISE AI solutions, you get:

  • Device Agnostic Performance
  • Integrated Image Quality Assessment
  • State-of-the-art Inference Core
  • Explainability
  • Ease of integration through RESTful APIs
  • Comprehensive Reporting
Video coming soon

FH-POISE™ Platform

Precision Ocular Intelligence
for Systemic & Eye Health

Our flagship AI platform analyzes retinal and anterior segment images to deliver multi-condition diagnostic insights — in real time, at point of care.

FH-POISE™ Platform
Core Features
01
Device Agnostic Performance
JPEG · PNG · DICOM
02
Integrated Image Quality Assessment
focus · uniformity · relevance
03
SOTA Inference Core
CNN · ViT · UNet
04
Explainability
GradCAM · Saliency · confidence
05
Ease of Integration through RESTFul APIs
REST · JSON · EMR · PACS
06
Comprehensive Reporting
PDF · JSON · Audit-trail
ACTIVE STAGE
AI systems that work across different devices with varied FOV, resolution, color tones
AI systems that work across different devices with varied FOV, resolution, color tones
AI systems that work across different devices with varied FOV, resolution, color tones
AI systems that work across different devices with varied FOV, resolution, color tones
AI systems that work across different devices with varied FOV, resolution, color tones
Poor image quality examples
Poor image quality examples
Poor image quality examples
Poor image quality examples
Good quality images but not relevant for specific conditions, e.g. Glaucoma
Good quality images but not relevant for specific conditions, e.g. Glaucoma
SOTA Inference Core
Heatmap localization of DR lesions
Optic nerve head analysis for Glaucoma using cup-disc segmentation
Tear breakup time analysis, auto-segmenting sectors that show break-up
ROP ridge localization
Artery/Vein segmentation and measurement for CVD assessment
Clean, well-documented API schema makes integration a breeze
Comprehensive Reporting
FH-POISE: Device Agnostic Performance
Image ingestion is usually device agnostic. This is achieved through extensive training on diverse image datasets. This allows image formats captured by a wide range of retinal cameras to be analyzed for pertinent conditions.
JPEG PNG DICOM Non-mydriatic Mydriatic Fundus Cameras
PIPELINE PROGRESS

AI Project Portfolio

Deployed models across
oculomics & systemic disease

Retinal DiseaseDeployed

Diabetic Retinopathy Grading ★ Flagship

95%+
Sensitivity
ICDR
Grading scale
5-class
Severity

Deep CNN classifier trained on 500K+ real-world screenings. Detects microaneurysms, hemorrhages, exudates, and neovascularization. Produces No DR → Proliferative scores with Grad-CAM heatmaps and macular edema co-detection.

EfficientNet-B4Multi-class classificationGrad-CAMMacular edema co-detection
Retinal DiseaseDeployed

Glaucoma Suspect Detection

CDR
Primary feature
RNFL
Layer analysis

Automated optic disc and cup segmentation with cup-to-disc ratio estimation. Identifies RNFL thinning and disc pallor indicative of glaucomatous damage. Outputs suspicion flag with segmentation overlay for referral triage.

Attention U-NetSegmentation + ClassificationCDR estimation
Retinal DiseaseDeployed

Age-Related Macular Degeneration

Drusen
Detection
Dry/Wet
Classification

Detects early, intermediate, and late AMD by identifying drusen deposits, geographic atrophy, and choroidal neovascularization. Supports dry vs. wet AMD differentiation to guide urgency of referral.

EfficientNet-V2Drusen segmentationAREDS grading
Retinal DiseaseDeployed

Cataract Detection & Grading

LOCS III
Reference scale

Detects lens opacity and grades cataract severity from retinal images using image quality degradation as proxy signal. Enables opportunistic cataract screening during routine retinal examination — no separate slit-lamp required.

Image quality regressionLens opacity scoringReferral calibration
Systemic BiomarkerDeployed

Hypertensive Retinopathy

KW
Keith-Wagener grading
4-class
Severity

Identifies vascular changes associated with systemic hypertension — arteriovenous nicking, silver/copper wiring, focal arteriolar narrowing. Non-invasive hypertension screening signal for community health programs.

ResNet-50Vascular feature extractionA:V ratio estimation
Systemic BiomarkerIn Validation

Cardiovascular Risk from Retina

Non-inv.
CVD screening

Leverages retinal vascular geometry — fractal dimension, vessel tortuosity, caliber asymmetry — as surrogate markers for CVD risk. Predicts composite cardiovascular risk score from fundus image alone, without blood tests or ECG.

Vision Transformer (ViT)Vascular geometryMulti-ethnic validation
Anterior SegmentDeployed

Lipid Layer Interferometry (LLI)

Dry Eye
Biomarker

Analyzes interference fringe patterns in the tear film lipid layer. Classifies lipid layer thickness and uniformity as an objective dry eye biomarker — replacing subjective grading with AI-scored metrics correlated with OSDI severity.

Texture CNNFringe pattern analysisOrdinal classification
Anterior SegmentDeployed

Tear Meniscus Height (TMH)

Sub-mm
Measurement precision

Automated measurement of tear meniscus height from anterior segment slit images using semantic segmentation. Provides an objective tear volume surrogate — a key parameter in the TFOS DEWS II dry eye diagnostic algorithm.

Semantic segmentationSub-pixel regressionDEWS II integration
Anterior SegmentDeployed

Meibomian Gland Dysfunction (MGD)

Gland
Morphology AI

Segments and quantifies Meibomian gland morphology from infrared meibography. Computes gland dropout score, tortuosity index, and gland density — fully automated pipeline replacing manual grader assessment.

Instance segmentationGland dropout scoringTortuosity index

Real-World Impact

From models to millions

Field-deployed across 65+ countries, our AI systems have processed hundreds of thousands of real patient screenings.

500K+
AI-analyzed retinal screenings
65+
Countries with deployed AI
9
AI models in production
6 yrs
Continuous AI R&D investment
Development Timeline
2018–2019

Foundations

First DR grading model trained on proprietary Forus fundus dataset. Proof-of-concept validated with clinical partners.

PatentA System and Method for Retinal Imaging
PatentAn Image Processing Method and Apparatus for Correcting an Image
2020–2021

Platform Expansion

Glaucoma detection, AMD, and cataract models added. FH-POISE platform architecture established.

PatentMethod and System for Enhancing Image Quality in Ophthalmic Imaging
PublicationEarly Detection of Diabetic Retinopathy Using Deep Learning on Fundus Images from Portable Non-Mydriatic Cameras
2022

Systemic Biomarkers

Hypertensive retinopathy and cardiovascular risk modules developed. Anterior segment AI work begins.

PatentA Method and System to Identify Intraocular Pressure (IOP) of an Eye
PublicationOptic Disc and Cup Segmentation for Glaucoma Screening in Low-Resource Settings
2023–2024

Anterior Segment AI

LLI, TMH, and MGD models deployed. Meibography segmentation launched. Dry eye AI suite complete.

PublicationAutomated Meibomian Gland Segmentation and Dropout Scoring Using Instance Segmentation Networks
PublicationAnterior Segment Imaging AI for Dry Eye Disease Grading in Community Screening
2025–Present

Scale & New Frontiers

500K+ screenings milestone. CVD validation ongoing. Exploring ROP, neonatal retinal AI, and LLM-assisted report generation.

PatentAI-Assisted Cardiovascular Risk Stratification from Retinal Vasculature (Filed)
Clinical Validation

Reader Equivalence Studies

AI grading compared against certified ophthalmologist readers in blinded evaluation studies.

Population-Level Calibration

Calibrated for South Asian, African, and East Asian populations.

Regulatory Alignment

Aligned with CDSCO, CE MDR, ABDM for SaMD. ISO 13485 development practices.


Press & Insights

Media Coverage & Blogs

Stories, features, and perspectives on Forus Health AI from global press and our own team.

Press The Hindu BusinessLine

Forus Health's AI eye-screening tool detects diabetic retinopathy with 95% accuracy

How a Bengaluru startup is bringing specialist-grade retinal diagnosis to Tier-3 clinics across India using portable fundus cameras and on-device AI inference.

March 2024 Read article
Press Economic Times

How AI is transforming eye care in rural India — the Forus Health story

A deep-dive into Forus Health's journey from ophthalmic hardware to AI-powered diagnostics, now deployed across 65 countries and screening millions of patients annually.

January 2024 Read article
Blog Forus Health AI

Inside FH-POISE: building a multi-condition inference pipeline for the real world

A technical walkthrough of our end-to-end AI pipeline — from non-mydriatic image capture and CLAHE pre-processing to EfficientNet-B4 inference and Grad-CAM explainability at the point of care.

November 2023 Read article
Press YourStory

Forus Health raises Series C to expand AI diagnostics platform globally

The ophthalmic AI company plans to use fresh funding to accelerate FH-POISE deployments across Southeast Asia, the Middle East, and Sub-Saharan Africa — targeting 5M screenings by 2025.

September 2023 Read article
Blog Forus Health AI

Oculomics: why the eye is the most powerful window into systemic disease

The retinal vasculature is the only place in the human body where blood vessels can be directly imaged non-invasively. Here's what that means for AI-powered cardiovascular, metabolic, and neurological screening.

July 2023 Read article
Press Mint

Made-in-India AI: Forus Health's retinal models clear CE and CDSCO regulatory hurdles

Regulatory clearances in Europe and India mark a milestone for Indian medical AI — validating FH-POISE as a clinically-safe, production-ready diagnostic platform for global deployment.

April 2023 Read article
Work With Us

Ready to build the
next medical AI
breakthrough?

We bring six years of production medical AI experience to new partnerships — diagnostics companies, hospital networks, research institutions, and global health organizations.

See Collaboration Model
Custom AI Model Development
End-to-end training, validation & deployment on your dataset
Clinical AI Validation
Multi-site studies, IRB-ready protocols, peer-review support
Medical Device Integration
SaMD-grade AI embedded into imaging hardware & platforms
Screening Program AI
Mass-scale telehealth & community screening deployments
Edge AI Deployment
TensorRT-optimized models for offline, low-resource settings
Multi-modal Health AI
Retinal + systemic biomarker fusion models & oculomics R&D
FAQ

Answers about
oculomics & AI

Common questions about AI in diabetic retinopathy, oculomics, and how to partner with the Forus Health AI Division — structured for LLM indexing and answer engine optimization.

Contact us
ai@forushealth.com
Bengaluru, India
What is oculomics and how does AI use it?
+

Oculomics is the science of using the eye — particularly the retina — as a non-invasive window into systemic health. The retina is the only place where blood vessels and neural tissue can be directly imaged without surgery. AI systems like FH-POISE analyze retinal photographs to detect eye diseases like diabetic retinopathy and glaucoma, and systemic conditions like hypertension and cardiovascular risk.

How does AI detect diabetic retinopathy from a fundus image?
+

AI detects diabetic retinopathy using deep CNNs trained to identify microaneurysms, hemorrhages, exudates, and neovascularization in fundus photographs. Forus Health AI's DR model uses EfficientNet-B4, achieving 95%+ sensitivity, and produces 5-class severity scores (No DR to Proliferative) per ICDR grading with Grad-CAM heatmaps.

What is the FH-POISE platform?
+

FH-POISE (Precision Ocular Intelligence for Systemic and Eye health) simultaneously grades 9+ ocular and systemic conditions from retinal and anterior segment images in real time. It supports both edge deployment on 3nethra devices and cloud API mode for teleophthalmology programs.

Can retinal imaging AI detect cardiovascular disease?
+

Yes. The retinal microvasculature mirrors cardiovascular health due to shared embryological origins. Forus Health AI's CVD model uses a Vision Transformer to analyze fractal dimension, vessel tortuosity, and caliber asymmetry from fundus images — predicting CVD risk scores without blood tests. Currently in multi-ethnic clinical validation.

How accurate is AI grading vs. an ophthalmologist?
+

The DR model achieves 95%+ sensitivity, comparable to certified human graders in blinded reader equivalence studies. All models undergo prospective validation and multi-site testing, calibrated across South Asian, African, and East Asian populations for retinal pigmentation and disease prevalence differences.

Is the platform compliant with medical device regulations?
+

Yes. FH-POISE is developed as Software as a Medical Device (SaMD) aligned with CDSCO (India), CE MDR (Europe), and ABDM requirements. Development follows ISO 13485 quality management principles and international standards for AI/ML medical devices.

Can I collaborate on a medical AI project?
+

Yes. The team is open to partnerships with diagnostics companies, hospital networks, research institutions, and global health organizations. Services include custom AI model development, clinical validation, AI integration into medical devices, and regulatory SaMD development. Contact: ai@forushealth.com

What is the difference between retinal AI and anterior segment AI?
+

Retinal AI analyzes the fundus (back of eye) to detect DR, glaucoma, AMD, hypertensive retinopathy, and systemic biomarkers. Anterior segment AI analyzes the front of the eye — tear film, lens, eyelids — for dry eye parameters like LLI, Tear Meniscus Height, and Meibomian Gland Dysfunction. Forus Health AI has production models in both domains.